Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
A qualitative urine immunoassay reports a category, even though the signal behind that category varies. Bang and colleagues tested the Triage TOX Drug Screen with standard materials near its cutoffs and compared results from 105 clinical urine specimens with a liquid chromatography–tandem mass spectrometry method. An estazolam control near the cutoff At the benzodiazepine cutoff…
In an LC–MS/MS method, structurally different cannabinoids can produce the same monitored ions. McRae and Melanson’s 17-analyte validation for cannabis and hemp illustrates why the chromatography deserves the same attention as the mass spectrometer. Look for the separation that matters The authors assessed cannabinoids with overlapping mass-spectrometric behavior and used retention time and chromatographic separation…
A SCRAM alcohol curve can peak well after breath alcohol peaks. The two instruments sample different signals, and the delay depends on what part of each curve you compare.
A veterinary case report distinguishes midazolam premedication, anesthetic maintenance and the milestones used to describe recovery.
A mixed-overdose case illustrates why a reported ingestion, a negative screening result, and a quantitative ethanol result carry different evidentiary weight.
Japanese surveillance found little aggregate change in benzodiazepine prescribing after a switch to three-month paliperidone. The mean and median told different stories.
An animal study used diazepam as a behavioral comparator and flumazenil to probe possible mechanisms of astaxanthin.
A mouse experiment measured loss and return of the righting reflex after diazepam. Housing conditions affected which sleep measures differed with the herbal preparation.
A randomized trial compared ciprofol with propofol after cardiac surgery. Midazolam was available in both groups as supplemental sedation.
A Japanese database study compared lacosamide and levetiracetam in patients who also received a benzodiazepine, separating the adjunctive comparison from first-line treatment.
A magnetoencephalography study associated benzodiazepine treatment with a steeper spectral slope, complicating the interpretation of that signal as a disease biomarker.
A human abuse-potential study found placebo-like drug liking at the lowest sunobinop dose, while higher doses produced a different profile and some performance effects remained at the low dose.
A case report documented improvement with lorazepam after catatonia emerged during recovery from acute illness following chemotherapy; the cause remained multifactorial.
A single-center abdominal-surgery study identified diazepam-use history as a delirium predictor, but prediction performance declined in a later validation cohort.
An Australian study associated prescription monitoring with changes in multiple-prescriber rates for monitored medicines, including benzodiazepines, without determining whether each episode represented misuse.
A nitrazepam formulation study reported large gains in aqueous solubility, but it did not measure blood concentrations, sedation onset, or clinical benefit.
A thirty-horse trial compared maintenance strategies rather than the effect of midazolam itself.
A mouse imaging study shows why tracer delivery and receptor-related uptake cannot always be read separately.
An unused multicenter paper compared treatments in children who were not eligible for the randomized RESCUE ESES trial.
A published implementation protocol specified intended outcomes rather than reporting completed tapering results.
A circuit experiment found effects opposite to those of several antidepressants at the tested concentrations.
A chemical-kindling experiment showed why a behavioral effect should not automatically be assigned to antioxidant action.
A narrative synthesis proposed complementary approaches within depression and anxiety care.
A flower-extract study explicitly separated anticonvulsant observations from an unconfirmed mechanism.
A scaffold-based antiviral study targeted viral spread rather than central sedation.
A cellular paper examined a naturally produced peptide rather than administration of a sedative medicine.
A large retrospective colonoscopy study measured procedural quality indicators without proving a sedative caused the differences.
A veterinary case reproduced an event under similar multidrug protocols without identifying its definitive cause.
A reported improvement followed introduction of lamotrigine and gradual withdrawal of several prior medicines.
A pediatric case describes stress reduction within a multicomponent cardiac anesthesia plan.