Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
A synthesis of randomized ICU trials found different advantages across outcomes rather than a universally superior sedative.
A poisoning study supports caution about negative urine screens, but one reported count must be reconciled before quoting its detection percentage.
A meta-analysis favored ketamine for selected suicidal-ideation outcomes, but midazolam’s role was to support a controlled comparison.
A community-pharmacy study demonstrates how a reassuring average can coexist with practical difficulties and inconsistent use.
A small retrospective study of stupor identified treatment associations without establishing an optimal medication regimen.
A Taiwanese pre-post study linked a historical payment change with different prescribing after hip-fracture hospitalization.
A multi-omics paper proposes a possible lorazepam-related target but does not establish that lorazepam treats or causes ovarian cancer.
A sleep-medication comparison in chronic kidney disease illustrates why a significant secondary outcome should not replace an uncertain composite result.
A probe-drug study found that an investigational drug could affect different metabolic pathways in opposite ways.
A hospital-based prediction model identified benzodiazepine exposure among variables associated with later cognitive impairment.
A retrospective machine-learning paper reported favorable associations for a fentanyl-midazolam regimen, but it did not assign treatments randomly.
A small observational study found different frontal EEG patterns in older adults with and without severe dementia at a similar clinical sedation target.
A national study found rising sedative-hypnotic prescribing before the pandemic as well as changes during it.
A case series supports feasibility of a conscious-sedation approach within a prepared specialist environment, not sedation without contingency planning.
A claims analysis found different responses to opioid policies across groups, but its benzodiazepine-overlap findings were narrower than its dose findings.
A perioperative study associated earlier midazolam administration with a different stress-biomarker pattern.
A wildlife anesthesia study found low oxygenation under both tested restraint combinations and improvement with supplemental oxygen.
A Thai primary-care analysis shows why the screening instrument matters when comparing prescribing prevalence.
A systematic review found evidence that diazepam can alter emotion processing, while leaving many other social-cognition questions unresolved.
A paper about nasal high flow during dental sedation describes a planned comparison, not evidence that the intervention succeeded.
A review of neuroleptic malignant syndrome reports suggests possible symptom improvement with lorazepam while leaving major efficacy uncertainty.
A scoping review examined ways to reduce harms among people who may not be seeking immediate benzodiazepine cessation.
A nationwide claims study associated Z-drug prescriptions with later tinnitus, but its exposure category must be named accurately.
A review and specialist survey found limited evidence for replacing clobazam during shortages, with variable proposed dose equivalence.
A pharmacokinetic review describes substantial context around remimazolam’s generally short action.
The supplied joint guideline treats physical dependence as a pharmacological adaptation that is distinct from a substance-use diagnosis.
A large meta-analysis found that the comparison anesthetic and the chosen emesis outcome changed the interpretation.
A brain-spectroscopy study examined withdrawal-related neurochemistry while recognizing that benzodiazepine requirements also reflect withdrawal severity.
A qualitative study examined recruitment to a midazolam-versus-melatonin trial rather than reporting which medicine worked better.
A national register analysis found substantial practice variation in long-term benzodiazepine prescribing after accounting for measured population differences.