A comparison between two combinations cannot isolate the contribution of midazolam.
A randomized cardiac-surgery study compared induction combinations in one hundred patients with impaired left-ventricular function. Most measured hemodynamic responses were similar, with some cardiac-index differences after intubation.
The patients underwent controlled elective care, and both groups received active combinations. Short-term physiological comparisons do not establish equivalence for all outcomes or safety in unstable emergency patients.
Describe the complete induction regimen and observation window. Do not attribute every pressure change or favorable response to one component. For a case review, preexisting cardiac function, concurrent drugs, airway interventions and timing remain necessary to evaluate an alleged anesthetic injury.
Source: PMC4493732, supplied full-text paper. Findings are paraphrased; case-review implications are an interpretation.
Related: Forensic Toxicology: expert analysis and case review.