A pediatric series reported successful reduction in 28 of 43 sedated attempts after earlier failures.
The protocol used ketamine, midazolam, and atropine during a later hydrostatic reduction attempt. Children with contraindications to hydrostatic reduction followed a different surgical pathway. The report described a 65.1% success rate among the 43 sedated procedures.
These were selected children at one institution without randomized assignment to sedation. Additional attempts, procedural experience, patient differences, and the three-drug regimen could all influence success. The data do not show how much midazolam independently contributed or establish that sedation should delay surgery in every case. The authors identified the small, nonrandomized design as a limitation. For a retrospective review, preserve the indication, prior attempts, contraindications, procedural response, and monitoring rather than equating the series’ success proportion with an individual probability.
Original analysis of the supplied journal article, identified as PMC7004751.