FORENSIC TOXICOLOGY

A 218-resident medication study used software and several screening criteria. The resulting flags were review prompts, not counts of proven benzodiazepine harm.

The assessment

Charts from one nursing home were screened with CheckTheMeds and three medication criteria sets. The proportion with a potentially inappropriate medication varied widely by tool. Benzodiazepines and proton-pump inhibitors were frequent entries.

Polypharmacy and potential interaction categories were associated with flagged prescribing. The criteria and software defined what was counted.

Validation questions remain

The study did not prospectively test whether acting on every flag reduced falls, hospitalization, or mortality. Potential interactions may not occur clinically, and some listed medications may have context-specific indications.

One facility and incomplete capture of nonprescription products limited generalization. For an individual case, obtain the exact rule, criteria version, medication list, and clinical rationale. A software alert cannot substitute for evidence that the relevant drugs were actually taken together or that a predicted interaction caused the observed event.

Source paper

Original analysis of the supplied journal article, identified as PMC9267842.

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